SARS-CoV-2 NSP3 Polyclonal Antibody (2019-nCoV)
This is a SARS-CoV-2 NSP3 (2019-nCoV) Virus Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling.
Synonyms
Non-structural protein 3, PL2-PRO, Papain-like proteinase, PL-PRO, Replicase polyprotein 1a
Reactivity
SARS-COV2
Immunogen
Recombinant SARS-CoV-2 NSP3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Virus Antibody
Applications
ELISA
Purification Method
Produced in rabbits immunized with purified, Recombinant SARS-CoV-2 NSP3 protein
Assay Type
Antibody
Concentration
0.33mg/mL
Dilution
ELISA 1:4000-1:8000
Buffer
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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