SARS-CoV-2 E Protein Polyclonal Antibody (2019-nCoV)
This is a SARS-CoV-2 E Protein (2019-nCoV) Virus Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Synonyms
2019-nCoV E protein,2019-nCoV sM protein, Envelope small membrane protein
Reactivity
SARS-COV2
Immunogen
Recombinant SARS-CoV-2 E protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Virus Antibody
Applications
ELISA
Purification Method
Produced in rabbits immunized with purified, Recombinant SARS-CoV-2 E protein
Assay Type
Antibody
Concentration
0.30mg/mL
Dilution
ELISA 1:4000-1:8000
Buffer
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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