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TIMP1 Polyclonal Antibody

This is a TIMP1 Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Synonyms

Clgi, Collagenase inhibitor, Collagenase inhibitor, Human, EPA, EPO, Erythroid Potentiating Activity, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, FLJ90373, HCI, Human Collagenase Inhibitor, Metalloproteinase inhibitor 1, Metalloproteinase inhibi

Swiss Prot

P12032

Reactivity

Mouse

Immunogen

Recombinant Mouse Timp1 protein expressed by E.coli

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

140kDa

Observed Molecular Weight

140,220kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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