SNCA Polyclonal Antibody
This is a SNCA Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release.Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores.Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis.Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5.
Synonyms
SNCA, NACP, PARK1, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor
Swiss Prot
P37840
Reactivity
Human, mouse, Rat
Immunogen
Recombinant Human SNCA protein expressed by E.coli
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
51 kDa
Observed Molecular Weight
51 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Frequently Asked Questions
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