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SNCA Polyclonal Antibody

This is a SNCA Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release.Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores.Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis.Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5.

Synonyms

SNCA, NACP, PARK1, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor

Swiss Prot

P37840

Reactivity

Human, mouse, Rat

Immunogen

Recombinant Human SNCA protein expressed by E.coli

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

51 kDa

Observed Molecular Weight

51 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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