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TGF beta Receptor I (TGFBR1) Polyclonal Antibody

This is a TGF beta Receptor I (TGFBR1) Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

TGFBR1, AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TGFR-1, tbetaR-I, TBRI, TBR-i

Gene ID

7046

Swiss Prot

P36897

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human TGF beta Receptor I

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% proclin300,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

22kDa/29kDa/34kDa

Observed Molecular Weight

34kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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