NOX2/gp91phox Polyclonal Antibody
This is a NOX2/gp91phox Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) . In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
Synonyms
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, IMD34, NOX2, p91-PHOX, CYBB
Gene ID
1536
Swiss Prot
P04839
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human NOX2/gp91phox
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
65kDa/66kDa/67kDa
Observed Molecular Weight
97-100KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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