ITGB3BP Polyclonal Antibody
This is a ITGB3BP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Synonyms
ITGB3BP, CENP-R, CENPR, HSU37139, NRIF3, TAP20
Gene ID
23421
Swiss Prot
Q13352
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ITGB3BP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
94kDa
Observed Molecular Weight
95kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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