CD146/MCAM Polyclonal Antibody
This is a CD146/MCAM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Synonyms
MCAM, CD146, MUC18, cell surface glycoprotein MUC18
Gene ID
4162
Swiss Prot
P43121
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human CD146/MCAM
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58kDa/73kDa/84kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Frequently Asked Questions
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