KCNQ2 Polyclonal Antibody
This is a KCNQ2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1) . At least five transcript variants encoding five different isoforms have been found for this gene.
Synonyms
KCNQ2, BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KV7.2
Gene ID
3785
Swiss Prot
O43526
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human KCNQ2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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