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IL1R2 Polyclonal Antibody

This is a IL1R2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.

Synonyms

IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB

Gene ID

7850

Swiss Prot

P27930

Reactivity

Human

Immunogen

Recombinant fusion protein of human IL1R2

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

39kDa

Observed Molecular Weight

45KDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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