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Topors Polyclonal Antibody

This is a Topors Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Functions as an E3 ubiquitin-protein ligase and as a E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA-damage-induced cell death through IKBKE sumoylation.

Synonyms

AW105885, LUN, TP53BPL, p53BP3/LUN, Topors

Gene ID

106021

Swiss Prot

Q80Z37

Reactivity

Mouse, Rat

Immunogen

A synthetic peptide of mouse Topors

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Observed Molecular Weight

70kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

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