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ACVRL1 Polyclonal Antibody

This is a ACVRL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Synonyms

ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I

Gene ID

94

Swiss Prot

P37023

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human ACVRL1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

46kDa/56-68kDa/74-83kDa

Observed Molecular Weight

83kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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