Proteinase 3/PR3 Polyclonal Antibody
This is a Proteinase 3/PR3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.
Synonyms
ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3, PRTN3
Gene ID
5657
Swiss Prot
P24158
Reactivity
Rat
Immunogen
Recombinant fusion protein of human Proteinase 3/PR3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
92 kDa
Observed Molecular Weight
110kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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