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RASD2 Polyclonal Antibody

This is a RASD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO) . This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD) . Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients.

Synonyms

Rhes, TEM2, MGC:4834, RASD2

Gene ID

23551

Swiss Prot

Q96D21

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human RASD2

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

11kDa

Observed Molecular Weight

10KDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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