TBC1D5 Polyclonal Antibody
This is a TBC1D5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
May act as a GTPase-activating protein (GAP for Rab family protein (s. May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN; the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes.
Synonyms
TBC1D5
Gene ID
9779
Swiss Prot
Q92609
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human TBC1D5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
32kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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