NFATC2IP Polyclonal Antibody
This is a NFATC2IP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
In T-helper 2 (Th2 cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity.
Synonyms
NFATC2IP, ESC2, NIP45, RAD60
Gene ID
84901
Swiss Prot
Q8NCF5
Reactivity
Human
Immunogen
Recombinant fusion protein of human NFATC2IP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
65kDa
Observed Molecular Weight
68kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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