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RASAL1 Polyclonal Antibody

This is a RASAL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described

Synonyms

RASAL1, RASAL

Gene ID

8437

Swiss Prot

O95294

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human RASAL1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

41kDa

Observed Molecular Weight

50kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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