HBG1 Polyclonal Antibody
This is a HBG1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1) . The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Synonyms
HBG1, HBG-T2, HBGA, HBGR, HSGGL1, PRO2979
Gene ID
3047
Swiss Prot
P69891
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human HBG1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44kDa/52kDa/54kDa/55kDa
Observed Molecular Weight
50kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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