ASH2L Polyclonal Antibody
This is a ASH2L Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.
Synonyms
ASH2L, ASH2, ASH2L1, ASH2L2, Bre2
Gene ID
9070
Swiss Prot
Q9UBL3
Reactivity
Human
Immunogen
Recombinant fusion protein of human ASH2L
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
61kDa/63kDa
Observed Molecular Weight
61kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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