KNSTRN Polyclonal Antibody
This is a KNSTRN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5-kinastrin (SKAP complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division. May be involved in UV-induced apoptosis via its interaction with PRPF19; however, these results need additional evidences.
Synonyms
KNSTRN, C15orf23, HSD11, SKAP, TRAF4AF1
Gene ID
90417
Swiss Prot
Q9Y448
Reactivity
Human
Immunogen
Recombinant fusion protein of human KNSTRN
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
5kDa/37kDa/51kDa/62kDa
Observed Molecular Weight
63kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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