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KNSTRN Polyclonal Antibody

This is a KNSTRN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5-kinastrin (SKAP complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division. May be involved in UV-induced apoptosis via its interaction with PRPF19; however, these results need additional evidences.

Synonyms

KNSTRN, C15orf23, HSD11, SKAP, TRAF4AF1

Gene ID

90417

Swiss Prot

Q9Y448

Reactivity

Human

Immunogen

Recombinant fusion protein of human KNSTRN

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

5kDa/37kDa/51kDa/62kDa

Observed Molecular Weight

63kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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