TNFRSF13C Polyclonal Antibody
This is a TNFRSF13C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE) . Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Synonyms
TNFRSF13C, BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin
Gene ID
115650
Swiss Prot
Q96RJ3
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human TNFRSF13C
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28kDa
Observed Molecular Weight
29kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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