RNF144B Polyclonal Antibody
This is a RNF144B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.
Synonyms
RNF144B, IBRDC2, PIR2, bA528A10.3, p53RFP
Gene ID
255488
Swiss Prot
Q7Z419
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human RNF144B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35kDa
Observed Molecular Weight
35kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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