ZFAND5 Polyclonal Antibody
This is a ZFAND5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF, IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Synonyms
ZFAND5, ZA20D2, ZFAND5A, ZNF216
Gene ID
7763
Swiss Prot
O76080
Reactivity
Mouse
Immunogen
Recombinant fusion protein of human ZFAND5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
11kDa
Observed Molecular Weight
12kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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