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MSL2 Polyclonal Antibody

This is a MSL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.

Synonyms

MSL2, MSL-2, MSL2L1, RNF184

Gene ID

55167

Swiss Prot

Q9HCI7

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human MSL2

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

113kDa/115kDa

Observed Molecular Weight

115kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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