MSL2 Polyclonal Antibody
This is a MSL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.
Synonyms
MSL2, MSL-2, MSL2L1, RNF184
Gene ID
55167
Swiss Prot
Q9HCI7
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MSL2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
113kDa/115kDa
Observed Molecular Weight
115kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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