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RNF166 Polyclonal Antibody

This is a RNF166 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Plays also a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.

Synonyms

RNF166

Gene ID

115992

Swiss Prot

Q96A37

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human RNF166

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

87kDa

Observed Molecular Weight

100kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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