TFCP2L1 Polyclonal Antibody
This is a TFCP2L1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs. With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity. Required for normal duct development in the salivary gland and kidney (By similarity. Coordinates the development of the kidney collecting ducts intercalated (IC and principal (PC cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity. Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity. Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity. JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity. Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity. Modulates the placental expression of CYP11A1.
Synonyms
TFCP2L1, CRTR1, LBP-9, LBP9
Gene ID
29842
Swiss Prot
Q9NZI6
Reactivity
Human
Immunogen
Recombinant fusion protein of human TFCP2L1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
49kDa/55kDa/57kDa
Observed Molecular Weight
58-65kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
