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MAP4K4 Polyclonal Antibody

This is a MAP4K4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

MAP4K4, FLH21957, HEL-S-31, HGK, MEKKK4, NIK

Gene ID

9448

Swiss Prot

O95819

Reactivity

Human

Immunogen

Recombinant fusion protein of human MAP4K4

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

298kDa/304kDa

Observed Molecular Weight

290kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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