RFTN1 Polyclonal Antibody
This is a RFTN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Involved in protein trafficking via association with clathrin and AP2 complex. Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly (I:C to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity. May regulate B-cell antigen receptor-mediated signaling. May play a pivotal role in the formation and/or maintenance of lipid rafts.
Synonyms
RFTN1, MIG2, PIB10, PIG9, RAFTLIN, raftlin
Gene ID
23180
Swiss Prot
Q14699
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human RFTN1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26kDa/62kDa
Observed Molecular Weight
75kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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