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Recombinant Caspase 8 Monoclonal Antibody

This is a Recombinant Caspase 8 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8.

Synonyms

ALPS2B, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein, Apoptotic cysteine protease, Apoptotic protease Mch-5, Apoptotic protease Mch5, CAP4, CASP-8, CASP8, CASP8, Caspase 8, Caspase 8 apoptosis related cysteine peptidase, Caspase-8 sub

Gene ID

841

Swiss Prot

Q14790

Reactivity

Hamster

Immunogen

A synthetic peptide of human Caspase-8

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

46kDa

Observed Molecular Weight

46kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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