Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody
This is a Recombinant Angiotensin II Type 1 Receptor Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Angiotensin II (Ang II), the main effector molecule of the renin-angiotensin system, exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1, also named as AT1R), thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone, cardiovascular function, salt and water homeostasis, AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease, from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .
Synonyms
AGTR1, AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R
Gene ID
185
Swiss Prot
P30556
Reactivity
Human
Immunogen
A synthetic peptide of human Angiotensin II Type 1 Receptor
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
312kDa
Observed Molecular Weight
160kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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