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Recombinant GSDMD Monoclonal Antibody

This is a Recombinant GSDMD Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Synonyms

DF5L, DFNA5L, FKSG10, GSDMDC1, GSDMD

Gene ID

79792

Swiss Prot

P57764

Reactivity

Human

Immunogen

Recombinant protein of human GSDMD

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

102kDa

Observed Molecular Weight

102kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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