PHOX2B Polyclonal Antibody
This is a PHOX2B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.
Synonyms
PHOX2B, NBLST2, NBPhox, PMX2B
Gene ID
8929
Swiss Prot
Q99453
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PHOX2B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
16kDa/17kDa
Observed Molecular Weight
20KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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