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PAI1 Polyclonal Antibody

This is a PAI1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU) . As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.

Synonyms

Plasminogen activator inhibitor 1, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PLANH1

Swiss Prot

P20961

Reactivity

Rat

Immunogen

Recombinant Rat PAI1 protein expressed by Mammalian

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

4.3mg/mL

Dilution

WB 1:250-1:500

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

26kDa

Observed Molecular Weight

28kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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