PAI1 Polyclonal Antibody
This is a PAI1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU) . As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.
Synonyms
Plasminogen activator inhibitor 1, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PLANH1
Swiss Prot
P20961
Reactivity
Rat
Immunogen
Recombinant Rat PAI1 protein expressed by Mammalian
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
4.3mg/mL
Dilution
WB 1:250-1:500
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26kDa
Observed Molecular Weight
28kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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