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CXCL4 Polyclonal Antibody

This is a CXCL4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CXCL4/PF4 is a secreted chemokine that is expressed by megakaryocytes and restrains the coagulation cascade. It is released by activated platelets and regulates Thrombin/Thrombomodulin complexes, activated Protein C (APC), Coagulation Factor Xa, and Fibrin. The anticoagulant heparin neutralizes CXCL4 procoagulant effects. Complexes of heparin and CXCL4 trigger antibody formation that causes the pathological syndrome HITT

Synonyms

CXCL4, SCYB4, Platelet factor 4, PF-4

Gene ID

5196

Swiss Prot

P02776

Reactivity

Human

Immunogen

Recombinant Human CXCL4 protein expressed by E.coli.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:1000-1:2000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

53kDa

Observed Molecular Weight

53kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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