LDHA Polyclonal Antibody
This is a LDHA Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
LDHA, also named as LDH-M and NY-REN-59, is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
Synonyms
Cell proliferation-inducing gene 19 protein, GSD11, L lactate dehydrogenase A chain, l7R2, LDH M, LDH muscle subunit, LDH1, PIG19 Proliferation-inducing gene 19
Swiss Prot
P00338
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human LDHA protein expressed by E.coli
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:2500-1:5000, IHC 1:200-1:400
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23kDa
Observed Molecular Weight
25kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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