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(KO Validated) PD-1/CD279 Polyclonal Antibody

This is a (KO Validated) PD-1/CD279 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Synonyms

PDCD1, CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Gene ID

5133

Swiss Prot

Q15116

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PD-1/CD279

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% proclin300,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

32kDa/34kDa

Observed Molecular Weight

32KDa/36KDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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