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NBS1/NBN Polyclonal Antibody

This is a NBS1/NBN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Synonyms

NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95, nibrin

Gene ID

4683

Swiss Prot

O60934

Reactivity

Human

Immunogen

A synthetic peptide of human NBS1/NBN

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000, IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

15kDa/21kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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