Bcdin3d Polyclonal Antibody
This is a Bcdin3d Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA (His, acting as a capping enzyme by protecting tRNA (His from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
Synonyms
AV138748, 4930556P03Rik
Gene ID
75284
Swiss Prot
Q91YP1
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of mouse Bcdin3d
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IF 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
125kDa
Observed Molecular Weight
126KDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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