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Recombinant Prohibitin Monoclonal Antibody

This is a Recombinant Prohibitin Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .

Synonyms

Epididymis luminal protein 215, Epididymis secretory sperm binding protein Li 54e, HEL 215, HEL S 54e, PHB, PHB, PHB1, Prohibitin

Gene ID

5245

Swiss Prot

P35232

Reactivity

Human, Rat

Immunogen

A synthetic peptide of human Prohibitin

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IHC-P

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000, IHC 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

57 kDa

Observed Molecular Weight

57 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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