Recombinant MLH1 Monoclonal Antibody
This is a Recombinant MLH1 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Synonyms
COCA 2, COCA2, DNA mismatch repair protein Mlh1, FCC 2, FCC2, hMLH 1, hMLH1, HNPCC 2, HNPCC, HNPCC2, MGC5172, MLH 1, MLH1, MLH1, MutL homolog 1 (E. coli), MutL homolog 1, MutL homolog 1 colon cancer nonpolyposis type 2, MutL homolog 1, colon cancer, nonpolyposis type 2 (E.
Gene ID
4292
Swiss Prot
P40692
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human MLH1
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000, IF 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29kDa
Observed Molecular Weight
24kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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