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Recombinant MCM2 Monoclonal Antibody

This is a Recombinant MCM2 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with mCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

Synonyms

BM28, CCNL 1, CCNL1, CDC like 1, cdc19, CDCL 1, CDCL1, Cell devision cycle like 1, Cyclin like 1, D3S3194, DNA replication licensing factor MCM2, KIAA0030, MCM 2, MCM2, MCM2 minichromosome maintenance deficient 2 mitotin, MCM2 minichromosome maintenance deficient 2 mito

Gene ID

4171

Swiss Prot

P49736

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human MCM2

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Recombinant Antibody

Applications

WB, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000, IF 1:50-1:200

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

110kDa

Observed Molecular Weight

210kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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