Recombinant Lamin A/C Monoclonal Antibody
This is a Recombinant Lamin A/C Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
Synonyms
70 kDa lamin, Cardiomyopathy dilated 1A (autosomal dominant), CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, Lamin A, Lamin A/C, Lamin A/C like 1, Lamin, Lamin C, Lamin-A/C, LDP1, LFP, LGMD1B, Limb girdle muscular dystrophy 1B (autosomal dominant), LMN 1, LMN A
Gene ID
4000
Swiss Prot
P02545
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human Lamin A/C
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC-P
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
14kDa
Observed Molecular Weight
16kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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