Recombinant IMPDH2 Monoclonal Antibody
This is a Recombinant IMPDH2 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Synonyms
IMDH2, IMP (inosine monophosphate) dehydrogenase 2, IMP dehydrogenase 2, IMP oxireductase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH-II, Impdh2, Inosine 5' monophosphate dehydrogenase 2, Inosine 5' phosphate dehydrogenase 2, Inosine monophosphate dehydrogenase type I
Gene ID
3615
Swiss Prot
P12268
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human IMPDH2
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC-P
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
115kDa
Observed Molecular Weight
150kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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