Recombinant CLSTN1 Monoclonal Antibody
This is a Recombinant CLSTN1 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Calsyntenins (calsyntenin-1, -2, -3) compose a family of neuronally expressed proteins that belong to the cadherin superfamily of cell adhesion molecules (PMID: 24966372; 12498782) . Calsyntenin-1 (CLSTN1) is a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. By binding Ca2+, calsyntenin-1 may modulate Ca2+-mediated postsynaptic signals (PMID: 11161476) . Calsyntenin-1 is a transmembrane cargo-docking protein for Kinesin-1-mediated vesicular transport (PMID: 16760430) . It can mediate axonal transport of the amyloid precursor protein and regulate Aβ production
Synonyms
CST-1, CSTN1, CDHR12, PIK3CD, ALC-ALPHA, XB31alpha, alcalpha1, alcalpha2
Gene ID
22883
Swiss Prot
O94985
Reactivity
Human, Mouse, Hamster
Immunogen
A synthetic peptide of human CLSTN1
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC-P
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
19kDa
Observed Molecular Weight
19kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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