Recombinant Keap1 Monoclonal Antibody
This is a Recombinant Keap1 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
KEAP1, also named as INRF2, KIAA0132 and KLHL19, is part of a multiprotein complex that contains the CUL3-ROC1 ubiquitin ligase, which can ubiquitinate the N-terminal domain of NRF2. Two molecules of KEAP1 bind to two distinct sites in the N-terminal region of NRF2, the ETGE and DLG sites, which affect the KEAP1-NRF2 interaction and/or its physiological consequences. KEAP1 retains NFE2L2/NRF2 in the cytosol. It functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. It also retains BPTF in the cytosol. This antibody is a mouse monoclonal antibody raised against residues near the C terminus of human KEAP1.
Synonyms
Cytosolic inhibitor of Nrf2, INrf 2, INrf2, Keap 1, KEAP1, KEAP1, Kelch like ECH associated protein 1, Kelch like family member 19, Kelch like protein 19, Kelch-like ECH-associated protein 1, Kelch-like protein 19, KIAA0132, KLHL 19, KLHL19, MGC10630, MGC1114, MGC20887, M
Gene ID
9817
Swiss Prot
Q14145
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human Keap1
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC-P
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000, IHC 1:20-1:50
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40kDa
Observed Molecular Weight
42kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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