Recombinant beta Catenin Monoclonal Antibody
This is a Recombinant beta Catenin Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CTNNB1, also known as β-Catenin, is an evolutionarily conserved, multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs, CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Synonyms
Beta catenin, Beta-catenin, Cadherin associated protein, Catenin (cadherin associated protein), beta 1,88kDa, Catenin beta 1, Catenin beta-1, CATNB, CHBCAT, CTNB1, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP0000016522
Gene ID
1499
Swiss Prot
P35222
Reactivity
Human, Mouse, Rat, Hamster
Immunogen
A synthetic peptide of human beta Catenin
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC-P
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
41kDa
Observed Molecular Weight
41kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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