Recombinant EGFR Monoclonal Antibody
This is a Recombinant EGFR Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
EGFR, also named as ERBB1, is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12, encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer.
Synonyms
Cell growth inhibiting protein 40, Cell proliferation inducing protein 61, EGF R, EGFR, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog), Epidermal growth factor receptor, erb-b2 receptor tyrosine kinase 1, ERBB, E
Gene ID
1956
Swiss Prot
P00533
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human EGFR
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000, IF 1:50-1:200
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
88kDa
Observed Molecular Weight
88kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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